May 2020. The coronavirus disease 2019 (COVID-19) pandemic reached Latin America later than other continents. The first case recorded in Brazil was on Feb 25, 2020. But now, Brazil has the most cases and deaths in Latin America (105 222 cases and 7288 deaths as of May 4), and these are probably substantial underestimates. Even more worryingly, the doubling of the rate of deaths is estimated at only 5 days and a recent study by Imperial College (London, UK), which analysed the active transmission rate of COVID-19 in 48 countries, showed that Brazil is the country with the highest rate of transmission (R0 of 2·81). Large cities such as São Paulo and Rio de Janeiro are the main hotspots now but there are concerns and early signs that infections are moving inland into smaller cities with inadequate provisions of intensive care beds and ventilators. Yet, perhaps the biggest threat to Brazil’s COVID-19 response is its president, Jair Bolsonaro. When asked by journalists last week about the rapidly increasing numbers of COVID-19 cases, he responded: “So what? What do you want me to do?” He not only continues to sow confusion by openly flouting and discouraging the sensible measures of physical distancing and lockdown brought in by state governors and city mayors but has also lost two important and influential ministers in the past 3 weeks.